Brand Cialis (Tadalafil)

Brand Cialis

Erectile Dysfunction (ED), also known as impotence, is a condition characterized by the inability to maintain an erection firm enough for sexual activity.

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Introduction

Erectile Dysfunction (ED), also known as impotence, is a condition characterized by the inability to maintain an erection firm enough for sexual activity. It is one of the common sexual dysfunctions in men of all age groups; under the age 40 experiencing it more.  As per the World Health Organization, over approximately 15% of men, each year are affected by ED.

Causes

The causes for ED include:

  • Insufficient blood flow in the penis.
  • Damaged nerves in the penis.
  • Stress or emotional disturbances
  • Smoking
  • Excessive alcohol consumption
  • Lacking physical activity
  • Chronic health conditions such as atherosclerosis, high blood pressure, diabetes and heart disease.

Sometimes, drugs used to treat other health conditions can have a negative impact on erection.

ED is a major sign of cardiovascular disease. Men with ED are at high risk of heart stroke, heart attack and other circulatory problems. ED also causes depression and distress for the man and his partner.

Diagnosis

  • Questionnaires – related to ED symptoms, personal life (reasons for stress, habits), and previous health history
  • Physical examination
  • Lab tests (blood test and urine test)
  • Other tests to check hormone levels

Treatment

Fortunately, a range of treatments is available to treat ED. Chemotherapy, hormone therapy, penile injections, intraurethral medication, vacuum erection devices, penile implants, and surgery.

Chemotherapy is the first line of therapy for ED.

About Cialis

Cialis is the brand name for tadalafil that is approved by the United States Food and Drug Administration (FDA) in 2003 for the treatment of ED. It is produced by Eli Lilly and Company. Cialis increases the blood flow into the penis and enables the erection of penis suitable enough for the sexual activity. The drug is effective and safe.

Brand Cialis 20mg tablet can also be used to treat pulmonary arterial hypertension and benign prostatic hyperplasia.

Dosage

Cialis tablets are yellow, film-coated tablets meant for oral use. They come in almond shape and are available in 5, 10 and 20 mg doses. In a man with low sexual activity, the first dose of 10mg is prescribed. The dosage is adjusted based on how the individual responds. The effect usually lasts up to 36 hours. If 10mg has not helped the patient in enough sexual activity, then a maximum 20mg single dose will be prescribed.

In a man with active sexual life, a dose of 5mg is prescribed and later reduced to 2.5mg depending on the response. Adjustment of doses depends on the user tolerability. However, only one dose per day is taken.

The drug should be taken at least 30 mins before the sexual activity.

Mechanism of Action

During sexual activity, nitric oxide that enables the production of cGMP is released into the penis. cGMP is mainly responsible for the blood flow into the penis and for the firm erection of the penis. In men with ED, an enzyme PDE5 destroys cGMP. Tadalafil stops the activity of PDE5. This causes the erection to last longer. In other words, the longer cGMP enzyme sustains during the sexual activity, the longer will be an erect penis, i.e., the blood flow into the penis will be for a longer time.

Side Effects

Cialis is a medication, with potentially serious adverse effects, and medical supervision is a must. The side effects include dizziness, nausea, muscle pain, nasal congestion, upset stomach, flushing and heartburn. Alcohol, hot weather or excessive physical activity may worsen the effects. In rare cases, Cialis Generic can cause difficulty in breathing, hypertension, and blurred vision and hearing loss.

Precautions

  • Do not take Cialis drug with nitrate-based drugs (cardiac drugs). ED drugs are not safe to take with nitrates as the combination could result in low blood pressure. People with angina, high or low blood pressure, previous history of stroke or any heart diseases should not take Cialis, especially without medical supervision.
  • Avoid using anti-fungal drugs or antibiotics when using Cialis.
  • Similarly, alpha-blocker drugs that many men take for urinary symptoms, also lower blood pressure. It is therefore recommended to take them at least four hours apart from ED drugs.
  • Avoid grapefruit or grapefruit juice when on Cialis medication.
  • Do not use Cialis if you have a kidney problem or liver problem. Keep your doctor updated with your previous medical history (leukemia, multiple myeloma, sickle cell anemia, etc.).
  • The drug is strictly not for women and children
  • Do not take the drug if you are allergic to tadalafil or any other component of the drug.
  • The drug should not be taken more than once within 24 hours of time.

 

Cost

The cost of Cialis original is high. In the United States, the cost of Cialis 20mg as of May 2019 is $1.91 and $7.65 for 2.5mg tablets.

The cost of the original drugs is usually high. This is because the manufacturers invest lots of money on research and testing of the drug or active components, designing, packaging, and advertising campaign which are very expensive. These costs get paid off by the high cost of the drug. On the other hand, generics do not spend the extra cost on any of these as they use the same formula as that of the brand drug.

Availability

Cialis Brand requires a doctor’s prescription. The drug is not provided without a prescription as it cannot be taken by everyone and unsafe for men with certain health conditions. You can buy brand Cialis online, from the comfort of your home, with a valid prescription or only after the online doctors review the case. Purchasing the medicine online can save both time and money. The drug can be purchased at best price using discount vouchers or coupons.